p1
stringlengths 9
246
| p2
stringlengths 10
231
| similarity
float64 0.09
1
|
|---|---|---|
CSc1nc2nc(C)c(CC(=O)N3CC(n4cc(C(C)(C)O)nn4)C3)c(C)n2n1 | Cn1ccnc1C(=O)N1CCCC[C@H]1c1ncc(Cc2cccc(Cl)c2)o1 | 0.680655 |
N#Cc1c(N2C[C@@H]3CN(S(=O)(=O)Cc4ccccc4)C[C@@H]3C2)nc2sccn12 | Cc1nc(NC(=O)[C@H]2CCCN2S(=O)(=O)c2c(C)noc2C)sc1-c1nccn1C | 0.771772 |
Cc1ccnc(N(Cc2cc(F)ccc2F)C(=O)OC(C)(C)C)c1 | O=C(Cn1c(=O)oc2ccccc21)N1CCC(N2CCc3ccccc3C2)CC1 | 0.566486 |
COc1ccc([C@H]2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC(C)C)[C@@H]3c2ccc(O)cc2)cc1OC | CC1(C)OC(=O)C(=C2CCCCN2)C(=O)O1 | 0.502155 |
O=C(c1ccccc1[C@@H]1CCNC1)N1CCS(=O)(=O)CC1 | O=C(OCc1cc(=O)n2c3c(sc2n1)CCCC3)[C@H]1CCCN1S(=O)(=O)c1ccccc1F | 0.530653 |
CCOC(=O)C1=C(C)Nc2ncnn2[C@H]1c1ccccc1Cl | Cc1nn(-c2ccccc2)c(C)c1NC(=O)CN(C)[C@@H]1CCCc2ccccc21 | 0.695522 |
Cc1noc([C@@H]2CCCN(C(=O)NCC#Cc3ccccc3)C2)n1 | C[C@H]1Cc2cc(-n3ccnc3-c3cc4n(n3)CCCNC4)ccc2O1 | 0.520964 |
COc1ccccc1OCCNC(=O)[C@@H]1CC(=O)Nc2ccccc21 | CN(C(=O)OC(C)(C)C)c1ncccc1[C@H]1CCCCN1 | 0.521445 |
O=C(C[C@H]1S/C(=N/N=C2/CSC(=O)N2)N(Cc2ccco2)C1=O)Nc1ccc(Cl)cc1 | CC(=O)Nc1cccc(NC(=O)c2nc(C)sc2-c2ccccc2Cl)c1 | 0.630252 |
CSc1ccccc1C(=O)NC[C@H]1Cc2cc(-c3nc(C)cnc3C)cc(F)c2O1 | COCCO[C@H]1[C@H](NC(=O)C(C)C)c2ccccc2C12CCNCC2 | 0.70911 |
C[C@H](NC(=O)[C@@H]1CCCN(S(=O)(=O)c2ccccc2)C1)C(=O)Nc1ccc(Cl)cc1 | CCOCCCNC(=O)c1ccc(N(CC)S(=O)(=O)c2ccccc2)cc1 | 0.533587 |
COc1ccc(NC(=O)COc2cc(C)nc(N3CCC(C)CC3)n2)cc1Cl | C=CCn1c(=O)c2c(nc3n(CCCOC)c(C)cn23)n(C)c1=O | 0.537902 |
COc1ccc(CN2C[C@H]3CCC[C@H](C2)C3(O)c2ncccc2C)cc1OC | COCCn1cnnc1CN(C)Cc1csc(C23CC4CC(CC(C4)C2)C3)n1 | 0.548212 |
COC(=O)c1ccc(NC(=O)COC(=O)[C@@H]2CC(=O)N(NC(=O)c3ccc(C)cc3)C2)cc1 | Cc1ccc(-c2ccc(OC(=O)c3ccc([N+](=O)[O-])cc3Cl)nn2)cc1C | 0.540204 |
COc1ccc2c(c1)CCC[C@@H]2n1cnc2cccnc2c1=O | CCCC[C@@H](CC)CNC(=O)[C@@H](C)N(c1ccc(OC)cc1)S(C)(=O)=O | 0.509169 |
CN(Cc1ccc(-n2cccn2)cc1)c1ncnc2c1CCC2 | COc1ccc(NC(=O)c2ccc3nnc([C@H]4CN(C(C)=O)CCN4C)n3c2)cc1 | 0.591729 |
COc1ccccc1NC(=O)[C@H](C)OC(=O)c1cc(C)nc2onc(C)c12 | Cc1cccc(CN2CCN(S(=O)(=O)c3c(C)nn(C(F)F)c3C)CC2)c1 | 0.590625 |
O=C(CNC(=O)c1ccccc1)N[C@@H]1CCOc2c(Cl)cccc21 | Cn1nc(C2CCN(C(=O)[C@H]3OCCc4ccccc43)CC2)c2nccnc21 | 0.557752 |
CO[C@H]1C[C@](N)(C(=O)Nc2cnn(-c3ccc(C)cc3C)c2)C1 | C[C@H]1C[C@@H](N(C(=O)c2ccco2)c2ccccc2)c2ccccc2N1 | 0.552575 |
O=C(CCn1cnc2sc3c(c2c1=O)CCCC3)OC[C@@H]1CCCO1 | COc1ccc(Cl)cc1C(=O)N1CCN(c2ccc3nncn3n2)CC1 | 0.622063 |
O=C(O)C[C@H]1CN(C(=O)c2cccc(Nc3cnccn3)c2)CCO1 | O=C(O)CN(C(=O)c1cncc(Br)c1)C1CCOCC1 | 0.503303 |
c1cc(-c2nc([C@@H]3CCOC3)no2)c2nccnc2c1 | Cn1cc(C(=O)NCCc2ccccc2)c(S(=O)(=O)N2CCN(c3cccc(Cl)c3)CC2)n1 | 0.585185 |
Cc1nccc(CCC(=O)N[C@@H]2c3ccc(F)cc3O[C@H]2C)n1 | CC(C)Oc1cccc([C@@H]2CC(=O)Nc3n[nH]cc32)c1 | 0.562921 |
CCN(CC)c1ccc(CNC(=O)c2ccnc(O[C@H]3CCSC3)c2)cn1 | O=C(Cn1ccc(O)nc1=O)N1CCCC[C@H]1c1ncc(Cc2cccc(F)c2)o1 | 0.54086 |
COc1ccccc1Nc1c2c3c(cccc3n(C)c1=O)C(=O)c1ccccc1-2 | CCN1C(=O)N/C(=C/c2ccc(OCc3ccccc3F)cc2)C1=O | 0.540404 |
O=C(c1ccc(Cl)cc1)[C@H]1[C@H]2C(=O)N(c3cccc([N+](=O)[O-])c3)C(=O)[C@@H]2[C@H]2c3ccccc3C=CN21 | COCCN1C(=O)C[C@@H](CN[C@H]2CCC[C@@H](C3CC3)C2)[C@@H]1c1cnn(C)c1C | 0.729811 |
COc1cc(Br)cc(Nc2nccn3cnnc23)c1 | COc1ccccc1CCNc1c(C)cnc2c1c(=O)n(C)c(=O)n2C | 0.530678 |
CN1/C(=C\C(=O)c2cc(S(=O)(=O)N3CCOCC3)c(Cl)cc2Cl)C(C)(C)c2ccccc21 | N#Cc1ccc(N2CCC[C@@H]2[C@@H]2COCC[C@@H]2O)cc1 | 0.513655 |
Cc1nc([C@H]2CCCN2C(=O)[C@H]2C[C@H]2c2ccc3c(c2)OCCO3)cs1 | O=C(CCN1C(=O)c2ccccc2S1(=O)=O)N1CC2(C1)OC[C@H]1C[C@@H]12 | 0.663926 |
CC[C@H](C)N(C(=O)Cn1c(=O)c(C#N)cn(CC)c1=O)[C@@H](C)CC | Cc1ccc(OCc2nc(C(=O)N(C)[C@@H]3CCS(=O)(=O)C3)cs2)cc1 | 0.504545 |
O=C(Nc1nc(CC2CC2)ns1)c1ccc2c(c1)CCCC2=O | COc1ccc(-c2noc(CN3C(=O)NC4(CCCCCC4)C3=O)n2)cc1 | 0.532902 |
CCOC[C@]1(C(N)=S)[C@H](c2ccc(OC)cc2)[C@H]1S(=O)(=O)c1ccc(C)cc1 | Cc1cc(C(=O)N2CCC3(CC2)C[C@@H]3N(C)Cc2nccs2)cc(O)n1 | 0.556712 |
Cn1c2c(cc(C(=O)N3CCC[C@H](c4ncc[nH]4)C3)c1=O)CCCC2 | CC(=O)NC[C@H]1Cn2cc(-c3ccc(C)cc3)nc2CO1 | 0.62 |
CC(C)c1csc(NC(=O)c2ccc(-c3ccc(Cl)cc3)[nH]c2=O)n1 | CCOC(=O)C1=C(O)C(=O)N(Cc2ccc(OC)cc2)[C@H]1c1cccnc1 | 0.628337 |
CCOC(=O)[C@H]1CCCN(C(=O)c2nc(-c3ccccc3)cs2)C1 | COc1ccnc(C(=O)N[C@@H]2C[C@H]3CO[C@@H](c4ccc(Cl)cc4)CN3C2)c1 | 0.545554 |
CO[C@@H](CNC(=O)C(=O)Nc1ccccc1C#N)c1ccsc1 | COc1ccc(NC(=O)C2=C(C)Nc3ncnn3[C@H]2c2ccc(OC)cc2OC)cc1 | 0.552254 |
COC(=O)C1=C(C)NC2=C(C(=O)C[C@@H](c3cccs3)C2)[C@H]1c1cc(OC)c(O)c([N+](=O)[O-])c1 | NC(=O)c1csc(N2CCn3c(Cc4c(F)cccc4F)nnc3C2)n1 | 0.77381 |
CCc1c(C)sc2[nH]c(=S)n(-c3ccc(O)cc3C)c(=O)c12 | COc1cc(/C=C2\C(=O)NC(=S)N(c3ccc(C(=O)O)cc3)C2=O)cc(OC)c1O | 0.705882 |
COc1cccc(NC(=O)COC(=O)[C@H]2CC(=O)N(c3ccc(Oc4ccccc4OC)cc3)C2)c1 | CC1=C(C(=O)Nc2ccc(C)cc2C)[C@@H](c2ccc(Cl)cc2Cl)NC(=O)N1 | 0.567398 |
COc1ccc(CCNC(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C)c2)cc1OC | COc1cccc2c(N(C)C[C@H]3COc4ccccc4O3)ncnc12 | 0.503341 |
CCOC(=O)C1=C(C)N=c2s/c(=C/c3ccsc3)c(=O)n2[C@H]1c1ccc(F)cc1 | CC[C@]1(C)NC(=O)N(NC(=O)CN2CC(n3cccn3)C2)C1=O | 0.634366 |
Cc1cc(N2CCN(C(=O)c3ccccc3)CC2)nc(N2CCCCC2)n1 | COc1cc(N2C[C@H](C)[C@@](O)(C3CC3)C2)nc(N)n1 | 0.541769 |
CC1(C)Cc2c(C#N)c(N)n(-c3ccccc3)c(=S)c2CS1 | COc1cccc(NC(=O)COC(=O)[C@@H]2CC(=O)N(c3cc(Cl)ccc3Cl)C2)c1 | 0.572928 |
O=C(Nc1cccnc1)c1ccc(Br)c(S(=O)(=O)N2CCOCC2)c1 | CCN1c2cc(Nc3ccc(C)cc3)c3c(c2NS1=O)C(=O)c1ccccc1C3=O | 0.579498 |
CSCC[C@@H](NC(N)=O)C(=O)Nc1ccc2c(ccn2CC(C)C)c1 | O=C([C@H]1CC(=O)N(c2ccccc2F)C1)N1CCC[C@H](c2n[nH]c3nccnc23)C1 | 0.553055 |
CN(C)C(=O)CO[C@@H]1CCN(C(=O)c2ccnc(F)c2)C[C@H]1Cc1ccccc1 | O=C(CSc1nnc(-c2ccc3c(c2)OCO3)o1)N[C@H](c1ccccc1)c1cccs1 | 0.503767 |
Cc1ccc(S(=O)(=O)N(C)c2ccc(Cl)c(C(=O)NCCCc3ccco3)c2)cc1 | Cc1ccnc(NC(=O)c2ccc3noc(-c4ccccc4)c3c2)c1 | 0.530187 |
CCOc1cc(/C=C2/SC(=S)N(CC(=O)O)C2=O)cc(Br)c1OCC | CC(C)[C@@H]1CN(C(=O)c2n[nH]c3c2CCC3)CCCN1CC1CC1 | 0.545552 |
Cc1cc(C(=O)Nc2ccc3c(c2)OCC(=O)N3)sc1-c1ccc(F)cc1 | O=S(=O)(c1ccc(F)c(F)c1)N1CCS[C@@H](c2ccccc2)CC1 | 0.513216 |
Cc1nc(O)c(C#N)cc1C(=O)N1CCC[C@]2(CCc3c[nH]nc32)C1 | Cc1nccc(N2CCN(C(=O)Nc3nc([C@@H]4C[C@H]5CC[C@H]4C5)cs3)CC2)n1 | 0.634021 |
Cc1cccc([C@@H](CN(C)C)NC(=O)c2cnn3cc[nH]c(=O)c23)c1 | O=C(CCN1C(=O)NC(C2CC2)(C2CC2)C1=O)c1ccc(F)cc1 | 0.569248 |
CN1C[C@@]2(CCCN(C(=O)c3ncccc3O)C2)OC1=O | O=C(Cc1ccc2c(c1)OCCO2)Nc1nnc(SCc2ccccc2F)s1 | 0.502787 |
O=S1(=O)C[C@@H](O)[C@@H](N(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)c(Cl)c2)C1 | COc1ccc(C)cc1S(=O)(=O)N1CCC[C@@H](C(=O)N[C@H](C)c2cc(C)c(C)cc2C)C1 | 0.652632 |
CCONC(=O)Cn1c(-c2ccc(F)cc2)c(C)sc1=O | CC(C)N1CCC[C@]2(CCCN2C(=O)c2cccc(-c3ccc(O)cc3)c2)C1=O | 0.545847 |
COc1ccccc1-c1nnc(SCC(=O)Nc2ccc(Cl)cc2C(F)(F)F)n1N | CN(C)[C@H]1CS(=O)(=O)[C@H]2CN(C(=O)c3ccc(N4CCCCC4)cc3)C[C@@H]12 | 0.614984 |
CC(C)(C)n1nnnc1[C@H](c1ccc(Cl)cc1)N1CCN(c2nc3ccccc3s2)CC1 | N[C@H]1CCCC[C@@H]1N/C=C1\C(=O)NC(=O)N(Cc2ccco2)C1=O | 0.565217 |
O=C(Nc1ccc(Cc2nnn[nH]2)cc1)c1cc(F)cc2[nH]cnc12 | CCN(CC)CCn1/c(=N/C(=O)c2c(F)cccc2Cl)[nH]c2ccccc21 | 0.580247 |
CC(=O)N1CC[C@@H](NC(=O)c2cc(C)nc3ccc(C)cc23)C1 | C[C@@H](OC(=O)Cc1n[nH]c(=O)c2ccccc12)C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 | 0.505482 |
COC(=O)c1cn(C2CCN([C@@H](C)c3nnnn3C3CC3)CC2)nn1 | Cc1ccc2c(nc3s/c(=C/c4cccs4)c(=O)n32)c1C | 0.597107 |
CCN(CC)c1ccc(/C=N\N2C(=O)[C@@H]3[C@@H]4C=C[C@H]([C@H]5C[C@H]45)[C@@H]3C2=O)cc1 | COc1cc2[nH]c3c(N4CCN(Cc5ccc6c(c5)OCO6)CC4)ncnc3c2cc1OC | 0.514595 |
O=C(NC(=S)Nc1cc(Cl)ccc1O)c1ccc(N2CCOCC2)c([N+](=O)[O-])c1 | COCCOc1ccc(CN2CCc3c(O)nc(-c4cnccn4)nc3C2)cc1 | 0.557917 |
CCOC(=O)c1c(NC(=O)COC(=O)C2(c3cccc(F)c3)CCCC2)oc(C)c1C(C)=O | Cc1nc2ccc(CN3CCC4(CC3)CC(C(=O)O)C4)cc2s1 | 0.531315 |
CC(=O)Nc1nc2c(ncn2[C@H]2O[C@@H]3[C@H](OC(=O)[C@H]3OC(C)=O)[C@@H]2OC(C)=O)c(=O)[nH]1 | COc1cccc(CN(C)CC(=O)N2C[C@@H](C(N)=O)Oc3ccccc32)c1 | 0.663317 |
O=C1C2=C(c3cc(OCc4ccccc4)ccc3O)CCCN2C(=O)CN1Cc1ccccc1 | O=C(/C=C/c1ccc(-c2ccc(F)cc2)s1)Nc1ccc2[nH]c(=O)[nH]c2c1 | 0.572181 |
CCN(CC)Cc1cnc2c(C(=O)N(C)C3CCOCC3)cnn2c1 | CCC[C@]1(CO)CCN(C(=O)c2cc3ccccc3c3cccnc23)C1 | 0.515337 |
COc1ccc2c(CC(=O)NCc3nn(C)cc3Cl)coc2c1 | C=CCn1c(SCCCCOC)nnc1-c1ccccc1OC | 0.519466 |
Cc1cc2ncc3c(n2n1)C[C@@H]1CC[C@@H]3N1C(=O)Cn1nc(C)nc1C | CCOc1ccc(Cl)cc1CN(C)C(=O)NC1(C(=O)O)CC1 | 0.530194 |
C[C@H]1Oc2ccccc2O[C@H]1C(=O)N1CC[C@@H](O)[C@H]1c1ccc(Cl)cc1 | C[C@@]1(c2cc(F)ccc2F)NC(=O)N(C[C@@H]2CCCCO2)C1=O | 0.653083 |
CS(=O)(=O)N(CC(=O)NCCCN1CCc2ccccc21)Cc1ccccc1 | O=C1/C(=C\c2ccccc2)SC(=S)N1[C@@H]1O[C@@H](CO)[C@@H](O)[C@@H](O)[C@H]1O | 0.541053 |
CC(C)n1ncc2cc(C(=O)N[C@@H](c3ccccc3)c3cccs3)cnc21 | O=C(NCc1ccco1)C(=O)NC[C@@H](c1ccc2c(c1)OCO2)N1CCN(c2ccccc2F)CC1 | 0.59597 |
C[C@H]1CCc2c(sc3ncnc(NCCc4ccccc4)c23)C1 | C=CCN1C(=O)CN(c2ccc(S(=O)(=O)N(C)C)cc2OC(C)C)C1=O | 0.648649 |
NS(=O)(=O)c1ccc(CCNC(=O)CCCCCn2nnc3ccccc3c2=O)cc1 | COc1ccc(C(=O)N2CCN(c3cc(-n4ccnc4C)ncn3)CC2)cc1OC | 0.546246 |
Cc1cnc(C)c(-c2cccc3c2O[C@@H](CNC(=O)c2cnn(-c4ccccc4)c2)C3)n1 | CN(C)Cc1nnc([C@H]2C[C@H](Nc3ccc4cccc(Cl)c4n3)C2)n1C | 0.612705 |
CCOc1ccc2nc(NC(=O)[C@@H](CC)Sc3nc(C)cc(=O)[nH]3)sc2c1 | CCn1c(CNC(=O)c2cccc([N+](=O)[O-])c2)nnc1SCC(=O)Nc1ccc(C(=O)OC)cc1 | 0.600212 |
COCCNC(=O)[C@H](c1ccccc1F)N(C(=O)Cn1nnc2ccccc21)c1ccccc1 | O=C(c1cnn(-c2cccc(Cl)c2)c1)N1CCC[C@@](O)(C(F)(F)F)CC1 | 0.56701 |
Cn1c(=O)c2c(nc(SCc3cccc4ccccc34)n2Cc2ccccc2Cl)n(C)c1=O | COc1ccc2c(c1)OC[C@]1(C(=O)O)CN(Cc3cncn3CC(C)C)C[C@H]21 | 0.74 |
CCOc1ccc([C@@H](CNC(=O)c2ccccc2OCc2ccccc2)N2CCOCC2)cc1OC | COc1ccc(-c2ccnc3nc(Nc4ccc(Cl)cc4)[nH]c(=O)c23)cc1 | 0.511111 |
O=C(NC1CC1)[C@@H]1CCCN1C(=O)[C@H]1CCCN(C(=O)Cc2ccccc2)C1 | COc1ccc(CCn2c(N)c(C(=O)NC[C@H]3CCCO3)c3nc4ccccc4nc32)cc1 | 0.501558 |
Cc1c(C(=O)Nc2ccc3c(c2)OCCO3)sc2nc3n(c(=O)c12)CCCCC3 | CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2ccc3c(c2)OCCO3)[C@@H]1c1ccc(OC)cc1OC | 0.827246 |
O=C(O)[C@H]1CN(c2ncccc2F)C[C@@H]1c1ccccn1 | O=c1[nH]c2nc(C(F)(F)F)cc(-c3ccccc3)c2c2ccccc12 | 0.531217 |
CCOC(=O)c1ccc2c(c1)[n+](CC(=O)Nc1cc(C(F)(F)F)ccc1Cl)c(C)n2CC | CC(C)c1nc(CNc2ncc(C(F)(F)F)cc2Cl)no1 | 0.515917 |
CCCc1nc([C@@H](NC(=O)N2CCC[C@@H](C)CC2)c2ccccc2)no1 | COc1ccc2c(c1[N+](=O)[O-])CCC/C2=N/OC(=O)c1ccccc1SC | 0.5383 |
Cn1c(C(=O)N2CCC[C@@H](COc3cccc(F)c3)C2)cc(=O)n(C)c1=O | COc1ccc2c(c1)OC(C)(C)C[C@@H]2NC(=O)[C@H](C)Oc1ccc2c(c1)CCCC2 | 0.599787 |
Cn1cnnc1[C@@H]1CCCN(C(=O)C2(Cc3cccc(F)c3)CCOCC2)C1 | CO[C@@H](C)c1noc(CN(C)C(=O)[C@]2(C(=O)O)C[C@H]3CC[C@H]2C3)n1 | 0.55902 |
COc1ccc([C@@H](NC(=O)C2CCN(C(=O)c3ccoc3)CC2)c2ccccc2)cc1 | Cc1cccc(N(C(=O)c2csnn2)[C@H](C(=O)NC2CCCCC2)c2ccc(C)o2)c1 | 0.522013 |
O=C(NCc1ccccc1OC(F)F)c1cc2ccccc2c(=O)[nH]1 | COCCn1c(=O)c2c(nc3n(-c4cccc(Cl)c4C)c(-c4ccccc4)cn23)n(C)c1=O | 0.556566 |
O=C1N=C(O)N(c2ccccc2)C(=O)/C1=C/NN1CCCC[C@H]1c1cccnc1 | Cc1cccc(C)c1NS(=O)(=O)c1ccc2c(c1)n(C)c(=O)n2C | 0.587137 |
Cc1cc(C(=O)CN2CCN(c3ncccn3)CC2)c(C)n1C[C@H]1COc2ccccc2O1 | O=C1C[C@@H](N2CCC(CCCc3ccccc3)CC2)C(=O)N1c1ccc(F)cc1 | 0.538961 |
Cc1ccc(NC(=O)COC(=O)CCCc2nc3ccccc3s2)cc1S(=O)(=O)N(C)C | O=C(c1ccc(Nc2ccccc2)c([N+](=O)[O-])c1)N1CCC(n2nnc3c2CCCC3)CC1 | 0.630021 |
C[C@H](Sc1nnc([C@@H](C)N(C)C)n1-c1ccc(F)cc1)C(=O)Nc1ccc(Cl)cc1F | CN(C[C@@]1(O)CCN(c2ncccn2)C1)C(=O)c1cccn1C | 0.590147 |
CCOC(=O)c1ccc2[nH]c(-c3ccc(O)c(OCC)c3)nc2c1 | CC(=O)N[C@@H](CC(=O)OCC(=O)N1c2ccccc2NC(=O)C1(C)C)c1ccccc1 | 0.523282 |
CN(C(=O)CCN1C(=O)c2ccccc2N2C(=O)CC[C@]12C)C1CCN(Cc2ccncc2)CC1 | CC(C)c1ccc(C(=O)N2CCC3(CCC3)S(=O)(=O)CC2)cn1 | 0.628245 |
COc1ccc(N2C(=O)CN(c3ccccc3F)C(=O)[C@@H]2c2ccc(N(C)C)cc2)cc1 | Cc1cccn2cc(C(=O)N[C@@H]3CCO[C@H](c4ccncc4)C3)cc12 | 0.567452 |
COC(=O)[C@H]1CCCC[C@]1(C)NC(=O)/C=C/c1cccc(OC)c1OC(F)F | Cc1nonc1NC(=O)c1oc2ccc(F)cc2c1C | 0.512679 |
Cc1cc(CN2CCN([C@H](C)C(=O)N3N=C(c4ccc(Cl)cc4)C[C@@H]3c3ccco3)CC2)no1 | CCOC(=O)N1CCC(NC(=O)c2ccc(-c3ccccc3)nc2C)CC1 | 0.579332 |
C=Cc1ccc(C(=O)N2C[C@@H]3CN(C4CCCC4)C[C@]3(C(=O)O)C2)cc1 | CC(=O)[C@H](C)CC(=O)N1CCOc2c(O)cc(-c3ccc(Cl)cn3)cc2C1 | 0.524775 |
CCS(=O)(=O)N(CC(=O)NCCSCc1ccccc1F)c1ccc2c(c1)OCCO2 | O=C(O)c1cnc(NCCc2cccs2)nc1-c1ccccn1 | 0.504994 |
CCS(=O)(=O)N1CCC(/N=C(/O)c2cnn3ccncc23)CC1 | O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)c1cn(Cc2ccccc2)nc1-c1cccnc1 | 0.600412 |
COC(=O)c1c(NC(=O)[C@@H]2C[C@H]3CC[C@@H]2C3)sc2c1CCC2 | COc1ccc(-c2ccc(=O)n(CC(=O)Nc3cccc4c3CCCC4)n2)cc1 | 0.662091 |
C[C@H]1Cc2ccccc2CN1C(=O)CCn1c(=O)oc2cc(Cl)ccc21 | Cc1ccc(OC[C@H]2CCN(S(=O)(=O)c3cccc4nsnc34)C2)nn1 | 0.626694 |
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