MeSH-CZ Datasets
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Czech translation of Medical Subject Headings - openly licensed under CC BY 4.0
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"flap" endonukleasy | endonukleázy, které odstraňují sekvence 5' dna ze struktury zvané dna flap. tato struktura se vyskytuje ve dvouřetězcové dna obsahující jednořetězcový zlom, kde je 5' část vlákna příliš dlouhá a překrývá 3' konec vlákna. flap endonukleázy štěpí řetězec směrem k 3'konci přesně za prvním spárovaným nukleotidem, čímž vzniká ligovatelný zlom | 0.5 | D |
( R)-6-(( S)-2-hydroxy-4-(4-hydroxyphenyl)butyl)-5,6-dihydropyran-2-one | from tapinanthus dodoneifolius | 0.3 | D |
(((2-(2-(2,4-dichlorophenyl)-4-(2-methyl-3-chlorophenyl)-1-ylmethyl)carbamoyl)methyl)-5-oxopyrrole-1-yl)-N-(3-piperidinylpropyl)acetamide | ccr4 antagonist | 0.3 | D |
(((4-(ethoxycarbonyl)phenyl)amino)(2,2,4,4-tetramethyl thiochroman-6-yl)amino) methan-1-one | a heteroarotinoid with antineoplastic activity | 0.3 | D |
(((4-(ethoxycarbonyl)phenyl)amino)(2,2,4,4-tetramethyl thiochroman-6-yl)amino) methane-1-thione | a heteroarotinoid with antineoplastic activity | 0.3 | D |
(((4-chloromethyl)benzoyl)amino)-tetramethylrhodamine | from a molecular probes | 0.3 | D |
(((5-(1,1-dimethylethyl)thiazol-2-yl)methyl)(((4-(4-(4-(1-propylbutyl)phenoxy)methyl)phenyl)thiazol-2-yl)methyl)amino)acetic acid | a hypoglycemic agent and ptp1b inhibitor | 0.3 | D |
((-)-4-(3-3,4-trans-p-menthadien-(1,8)-yl)-orcinol) | stimulates endothelial cell migration via a gi/go-coupled receptor distinct from cb1, cb2 or edg-1; do not confuse with o-1918 (anisole) | 0.3 | D |
((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol | 16x more potent than labetalol in beta-adrenergic receptor blockade & lowered blood pressure in spontaneously hypertensive rats | 0.3 | D |
((1-((2-amino-9H-purin-9-yl)methyl)cyclopropyl)oxy)methylphosphonic acid dipivoxyl | an anti-hepatitis b agent | 0.3 | D |
((1-aminoethyl)iminobis(N-(oleicylcysteinyl-1-amino-ethyl)propionamide)) | eco compound; consisting of protonatable ethylenediamine (e) head group, two cysteine (c) functional linkers and two oleoyl (o) lipophilic tails; used for synthesis of gene delivery nanoparticles | 0.3 | D |
((1-aza-4-methyl-6-(1,2,2,4-tetramethyl(1,2-dihydroquinolyl))hexa-1,3,5-trienyl)amino)aminomethane-1-thione | inhibits growth of mycobacterium bovis | 0.3 | D |
((1-ethylpyrrolidin-2-yl) methyl)-4-hydroxy-7-methoxy-quinoline-3-carboxamide | an immunologic adjuvant | 0.3 | D |
((1-methyl)ethoxycarbonyloxy)-ethyl 7-(2-(2-amino-4-thiazole)-2-methoxyaminoacetamido)-3-(2-propenyl)-3-cephem-4-carboxylate | prodrug to 3-(2-propenyl)cephalosporins; ; rn given is for (6r-(2(r*),6alpha,7beta(z))-isomer | 0.3 | D |
((18)F)PI-2620 | tau pet tracer | 0.3 | D |
((1E)-2-((2S)-1,2,5-trimethylbicyclo(3.2.l)octan-8-yl)vinyl) benzene-3-carboxylic acid | isolated from the aerial parts of jasonia montana | 0.3 | D |
((1E)-3-((7R)-1,7-dimethy-4-methylenecycloheptanyl)prop-1-enyl) benzene-3-carboxylic acid | isolated from the aerial parts of jasonia montana | 0.3 | D |
((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester | calpain inhibitor | 0.3 | D |
((1S)-1-(((7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl)amino)ethyl)phosphonate | a glycine site-specific n-methyl-d-aspartate receptor antagonist prevents activation of the nmda/no/cgmp pathway by ammonia | 0.3 | D |
((2,2',2'',2'''-(4'-)(((4,6-dichloro-1,3,5-triazin-2-yl)amino)biphenyl-4-yl)-2,2':6',2''-terpyridine-6,6''-diyl)bis-(methylenenitrilo))tetrakis(acetato)europium(III) | a luminescent lanthanide chelate label | 0.3 | D |
((2,2'-6',2''-terpyridine)ruthenium(chloro)(2,3-bis(2-pyridyl)pyrazine)(dichloroplatinum)) | binds dna | 0.3 | D |
((2,3,7,8,12,13,17,18-octakis(benzylthio)-5,10,15,20-tetraazaporphyrin))nickel(II) | an ionophore used to screen thiocyanate ion | 0.3 | D |
((2,3-difluorobenzyl) 5-fluoroacetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-d-glycerogalacto-2-nonulopyranosid)onic acid | a mylein-associated glycoprotein antagonist | 0.3 | D |
((2,6-bis(1-methylethyl)phenoxy)sulfonyl)carbamic acid 2,6-bis(1-methylethyl)phenyl ester | a water soluble inhibitor of acat | 0.3 | D |
((2-hydroxy-1-naphthaldehyde)-3-isatin)-bishydrazone | a chelating agent | 0.3 | D |
((2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diazabenzo(a)azulene-3-carbonyl)amino)acetic acid | inhibits hypoxia-inducible factor hydroxylase | 0.3 | D |
((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid | an anion channel blocker | 0.3 | D |
((3)H)(S)-2-((S)-3-acetylamino-3-sec-butyl-2-oxo-pyrrolidin-1-yl)-N-((1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzylamino)-propyl)-4-phenyl-butyramide | a tritiated ligand for the characterization of bace1 inhibitors | 0.3 | D |
((3,4-(methylenedioxy)benzyl)amino)-6-chloroquinazoline | a phosphodiesterase type y inhibitor | 0.3 | D |
((3-((2R)-(((2R)-3-chlorophenyl)-2-hydroxyethyl)amino)propyl)-1H-indol-7-yloxy)acetic acid | tak-677 is also reported as aj-9677 | 0.3 | D |
((3-bromo-7-cyano-2-naphthyl)(difluoro)methyl)phosphonic acid | a potent and orally active small molecule ptp1b inhibitor | 0.3 | D |
((3-hydroxy-6-pyridinyl)methyl)cytisine | isolated from the stem bark of maackia amurensis | 0.3 | D |
((3-indolylmethylene)hydrazono)indolin-2-one | has pro-apoptotic and anti-proliferative effects on tumor cell lines | 0.3 | D |
((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine | a mu opioid receptor ligand | 0.3 | D |
((3alpha,3'alpha,4beta,4'beta)-3,3')-dimethoxy-cis-(4,4'-bis(3,4,5,10-tetrahydro-1H-naphtho(2,3-)pyran))-5,5',10,10'-tetraone | pyranonaphthoquinone from the roots of pentas longiflora (rubiaceae) | 0.3 | D |
((4'-benzoyl)phenoxy)glucopyranoside | a photoaffinity probe for studying the sodium d-glucose cotransporter | 0.3 | D |
((4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methylpyrrolo(1,2-f)(1,2,4)triazine-6-carbonyl)(propyl)carbamoyloxy)methyl-2-(4-(phosphonooxy)phenyl)acetate | a prodrug of bms-582949 | 0.3 | D |
((4-methoxybenzoyl)oxy)acetic acid | inhibits amide synthetase | 0.3 | D |
((4-methoxyphenyl)carbonyl)-valyl-N-(3-(1,1,1-trifluoro-2-hydroxy-4-methylpentyl))prolinamide | inhibits human neutrophil elastase | 0.3 | D |
((4-methyl(1,2,4)triazolo(4,3-a)quinolin-1-yl)sulfanyl)acetic acid | an antitubercular agent that inhibits n-acetylglucosamine-1-phosphate uridyltransferase | 0.3 | D |
((4-tert-butylcyclohexylidene)methyl) (4-methoxystyryl) sulfide | has antioxidant activity | 0.3 | D |
((5-(2-methylbenzothiazol-5-yloxymethyl)isoxazole-3-carbonyl)amino)phenylacetic acid methyl ester | an antitubercular agent | 0.3 | D |
((5-(adenin-9-yl)-2-furyl)methoxy)methyl phosphonic acid | an adenylate kinase ak2 inhibitor | 0.3 | D |
((5-nitrofuran-2-yl)methyl-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl 4-chlorobutyl(methyl)phosphoramidate) | inhibits geranylgeranyl transferase | 0.3 | D |
((5Z)-5-(4-hydroxy-3-methoxy-phenyl)methylene)thiazolidine-2,4-dione | a partial peroxisome proliferator-activated receptor gamma agonist; ; do not confuse with ns-1, a benzoic acid | 0.3 | D |
((6-ethyl-7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-ylmethyl)methylamino)acetic acid | an ampa/gly(n) receptor antagonist | 0.3 | D |
((7-chloro-3-(2-fluorophenyl)-1,2-benzisoxazol-6-yl)oxy)acetic acid | rn given from first source | 0.3 | D |
((7R)-7-(((4-fluorophenyl)sulfonyl)(methyl)amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)acetic acid | a chemoattractant receptor-homologous molecule expressed on t-helper type 2 cells (crth2) and prostaglandin d2 receptor antagonist | 0.3 | D |
((Dha)7)-microcystin-RR | hepatotoxic microcystin from microcystis aeruginosa strain 205 | 0.3 | D |
((E)-(5)-(3,5-di-tert-butyl-4-hydroxybenzylidene)- 2-ethyl-1,2-isothiazolidine-1,1-dioxide) | a cyclooxygenase-2 inhibitor | 0.3 | D |
((E)-N-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butyl)-3-phenylacrylamide | a dopamine antagonist; selective for d3 dopamine receptors | 0.3 | D |
((ENB-3-isopropoxy-PIDMP)Ga(III)) | used to monitor the activity of breast cancer resistance protein | 0.3 | D |
((G4)-PGLSA-OH)2-PEG3400 dendrimer | pglsa - poly(glycerol-succinic acid); a fourth generation dendrimer | 0.3 | D|E|J |
((H2O)(terpy)Mn(mu-O)2Mn(terpy)(OH2))(NO3)3 | terpy = 2,2':6,2''-terpyridine | 0.3 | D |
((Phen)(2)Ru(tatpp)Ru(phen)(2)) | an intercalating agent | 0.3 | D |
((Py-3')TPP-Ru(phen)2Cl)Cl | a ruthenium porphyrin complex; (py-3')tpp=5-(3'-pyridyl-10,15,20-triphenylporphyrin; phen = 1,10-phenanthroline | 0.3 | D |
((Ru(Me2bpy)2)2(mu-bpm))4 | bpm = 2,2'-bipyrimidine; me2bpy = 4,4'-dimethyl-2,2'-bipyridine | 0.3 | D |
((S)-2-(5-(1,2-dihydro-3-methyl-1-oxobenzo(f)-quinazoline-9-yl)methyl)amino-1-oxo-2-isoindolynyl)-glutaric acid | a liposomal thymidylate synthase inhibitor | 0.3 | D |
((Z)-1-thiophen-2-ylethylideneamino)thiourea | inhibitor of severe acute respiratory syndrome coronavirus entry | 0.3 | D |
((azidophenyl)ureido)taxoid | a photoaffinity probe for the taxoid binding site on microtubules | 0.3 | D |
((dihydroindenyl)oxy)alkanoic acid | inhibitor of k+cl- cotransport system | 0.3 | D |
((eta6-p-cymene)Ru(4,4,4-trifluoro-1-(4-chlorophenyl)-1,3-butanedione)-1,3,5-triaza-7-phosphaadamantane) | has antineoplastic activity | 0.3 | D |
((hydroxymethylhexadecanoyl ester)ethylenepropylene triaminepentaacetic acid)gadolinium(III) | a putative mri contrast agent; structure of ligand in first source | 0.3 | D |
((nitrilotri(methylene))triphosphonato)cuprate | rn given refers to tetra-k salt | 0.3 | D |
((nitroveratryl)oxy)chlorocarbamate | an amino group-directed photo-deprotection reagent; (-nh- in carbamate omitted?) | 0.3 | D |
((p-(N-acrylamino)phenyl)mercuric chloride) | reacts with thiol groups of proteins | 0.3 | D |
(+)-(7R,8R)-4-hydroxy-3,3',5'-trimethoxy-8',9'-dinor-8,4'-oxyneoligna-7,9-diol-7'-aldehyde | from the stems of euonymus oblongifolius | 0.3 | D |
(+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid | a gaba-b receptor antagonist | 0.3 | D |
(+)-11alpha-hydroxyerythravine | erythrinian alkaloid derivative from the flowers of erythrina mulungu | 0.3 | D |
(+)-13-stemarene | from plants of the genus of stemodia | 0.3 | D |
(+)-18-deoxystemarin | from plants of the genus of calceolaria | 0.3 | D |
(+)-2-deoxyoryzalexin S | isolated in chile from calceolaria species | 0.3 | D |
(+)-3'alpha-angeloxy-4'-keto-3',4'-dihydroseselin | anti-inflammatory | 0.3 | D |
(+)-3-carene synthase, Picea abies | a methyl jasmonate-induced terpene synthase from norway spruce (picea abies); genbank af461460 | 0.3 | D |
(+)-4-(3-((1-(4-chlorophenyl)-2-oxo2-(6-(trifluoromethoxy)indolin-1-yl)ethyl)amino)-5-methoxyphenoxy)butanoic acid | dengue virus inhibitor | 0.3 | D |
(+)-5-epi-eudesm-4(15)-ene-1beta,6beta-diol | originally from litsea | 0.3 | D |
(+)-Larreatricin hydroxylase, creosote bush | an enantio-specific polyphenol oxidase; mw 43 kda; genbank ay370019 | 0.3 | D |
(+)-N-benzoylbuxahyrcanine ((20S)-3beta-benzoylamino-20-dimethylaminobux-9(11)-ene-10alpha-ol) | triterpenoid alkaloid cholinesterase inhibitor from buxus hyrcana | 0.3 | D |
(+)-N-deoxymilitarinone A | a neuritogenic pyridone alkaloid from the insect pathogenic fungus paecilomyces farinosus | 0.3 | D |
(+)-N-isobutyroylbuxahyrcanine ((20S)-20-(dimethylamino)-3beta-(2'-methylpropanoyl)bux-9(11)-en-10alpha-ol) | triterpenoid alkaloid cholinesterase inhibitor from buxus hyrcana | 0.3 | D |
(+)-N-tigloylbuxahyrcanine ((20S)-20-(dimethylamino)-3beta-(2'-methyl-2'-butenoylamino)bux-9(11)-en-10alpha-ol) | triterpenoid alkaloid cholinesterase inhibitor from buxus hyrcana | 0.3 | D |
(+)-alpha-hydroxyerysotrine | erythrinian alkaloid derivative from the flowers of erythrina mulungu | 0.3 | D |
(+)-erythravine | erythrinian alkaloid derivative from the flowers of erythrina mulungu | 0.3 | D |
(+)-methyl 2-((4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)methyl)-1-phenylcyclopropanecarboxylate | a sigma receptor ligand | 0.3 | D |
(+)-perseanol | isoryanodane diterpene that is isolated from the tropical shrub persea indica | 0.3 | D |
(+)-przewalskin | a bridged abietane diterpene isolated from salvia przewalskii | 0.3 | D |
(+)6a-hydroxymaackiain 3-O-methyltransferase | terminal step for synthesis of the phytoalexin pisatin in pisum sativum; amino acid ; genbank u69554 | 0.3 | D |
(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine | rn given refers to (+-)-isomer | 0.3 | D |
(+-)-(1'R*,2'S*,6'R*)-(2-hydroxy-4,6-dimethoxyphenyl)(3'-methyl-2'-(3''-methylbut-2''-enyl)-6-phenylcyclohex-3'-enyl)methanone | factor xa inhibitor | 0.3 | D |
(+-)-11-hydroxynoraporphine | dopaminergic cpd | 0.3 | D |
(+-)-E-4-methyl-2-((E)-hydroxylamino)-5-nitro-6-methoxy-3-hexanamide | a carcinogen | 0.3 | D |
(+-)-huprine Z | an anticholinesterase inhibitor | 0.3 | D |
(-)(2S)-5,6,7,3',5'-pentahydroxyflavanone-7-O-beta-D-glucopyranoside | anti-inflammatory and cytotoxic cpd from lippia graveolens | 0.3 | D |
(-)-(1'R,2'S)-erythro-5-hydroxy-7-(1',2'-dihydroxypropyl)-2-methylchromone | from berchemia lineata | 0.3 | D |
(-)-(1R,4R)-1,4-(2,3)-indolmethane-1-methyl-2,4-dihydro-1H-pyrazino-(2,1-b)quinazoline-3,6-dione | cytotoxic and antifungal alkaloid produced by penicillium vinaceum, an endophytic fungus from crocus sativus | 0.3 | D |
(-)-(1S)-15-hydroxy-18-carboxycembrene | from the roots of euphorbia pekinensis rupr | 0.3 | D |
(-)-(2R*,3S*,6S*)-N,2-dimethyl-3-hydroxy-6-(9-phenylnonyl)piperidine | isolated from the rhizomes of arisaema decipiens schott (araceae), a traditional antitumor herb used by the dong people | 0.3 | D |
(-)-(7R,8S)-(4-hydroxy-3-methoxyphenylglycerol 9-O-β-D-(6-O-4-hydroxy-3-methoxybenzoyl))-glucopyranoside | from bamboo shoots (phyllostachys pubescens) | 0.3 | D |
(-)-14-hydroxygelsenicine | 14-hydroxygelsenicine-related gelsemium alkaloid | 0.3 | D |
(-)-5-(3',4',5'-dihydroxyphenyl)-valerolactone | metabolite of catechins | 0.3 | D |
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MeSH-CZ-2025-notes - training dataset
Czech translation of Medical Subject Headings version 2025
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